Curcumin attacks multiple targets, providing the scientific basis for its effectiveness in many different diseases. Extensive research shows most diseases are caused by dysregulation of multiple signaling pathways--casting doubt on the effectiveness of monotherapy, which is limited to a single target. (2, 6)
Studies show curcumin modulates numerous molecular targets, including: regulating several cytokines and fibroblast growth factor-2 (gene expression), growth-factor receptors including modulation of androgen receptors (protein kinases), transcription factors, pro-inflammatory enzymes (including supression of COX-2, 5-LOX and iNOS and regulation of NF-?B), modulation of cell-cycle-related gene expression, blocking the adhesion molecules, downregulating antiapoptic proteins and inhibiting multi-drug resistance.
turmeric, and makes up about 6% of the spice.
While therapeutic properties of turmeric have been known for centuries, modern science has identified the curcuminoids (phenolic compounds found in turmeric) and provides a scientific basis for many clinical uses of standardized curcumin.
Extensive research shows curcumin can benefit multiple targets in your body and provides scientific basis for its effectiveness in a wide variety of different body systems.